HE'S more used to posing around Seattle Grace Mercy Hospital, rattling off sharp one-liners to beautiful colleagues in wards resembling showhomes.
So when Grey's Anatomy star Kevin McKidd pitches up wearing his medical scrubs in the tired wards of a former cancer unit in Glasgow, there's a dream-like contrast - a momentary mash-up between the Western Infirmary and US Medicare.
It takes for Sanjeev Kohli to walk past to ground this experience firmly in Glasgow.
Kevin leads an impressive ensemble cast in an off-beat new BBC Scotland production called One Night In Emergency. It's the first piece of TV work from the pen of Gregory Burke, who is best known for international theatre hit Black Watch.
The drama follows Kevin's character Peter on a bizarre journey through an inner city hospital as he desperately searches for his wife, Penny, played by Michelle Ryan.
It's a radical change of direction for Kevin, whose breakthrough role in Trainspotting wasn't the instantaneous career launchpad it proved to be for some of his co-stars in the 1996 film.
Instead he opted for the slow burn, working his way through a CV's worth of smaller parts before finally bubbling up in the big time across The Pond in epic swords and sandals series Rome.
By all accounts, the BBC had to work hard to bring him home for the part in a comparatively low-budget production.
For Kevin, though, it represented a chance to get home from the incessant sunshine of LA, where he lives with his wife and young family.
That's right. A break from the sun. Kevin, originally from Nairn, said: "When I'm here, of course, I miss the sun of LA but, believe it or not, it's actually nie to get a break from the sun too.
"It becomes a bit of a bore after a while. You actually find yourself yearning for wind or rain or something.
"When I lived in London, I liked that you could jump in the car and drive to Scotland in a few hours. Now that I'm in LA that's not possible. So it was nice this part gave me the chance to come back.
"I've been looking for a home-grown Scottish-based project for a couple of years. The last I did here was (low-budget) flick Afterlife, which was a good few years ago. Then this came up.
"I know Gregory Burke is the big hot property of the moment after Black Watch, but I think I must be about the only person who hasn't seen it.
"I tried to get tickets for it when it was in LA, but things were really tight with filming, so I never got the chance."
Fans of the play, which toured the world with the National Theatre of Scotland, might note the irony that Kevin features in Burke's script.
One of the characters in the play is said to look like the actor, with a joke over whether his hair is blond or ginger.
Kevin said: "It's blond. They actually dyed it for the part in Grey's Anatomy, and it ended up ginger. But it's naturally blond.
"One of my pals told me that I was mentioned in Black Watch, and I was dead chuffed.
"Gregory said the reason that ended up in there was because when he did his research with the troops, they all loved the film Dog Soldiers (which Kevin starred in). They watched it all the time on DVD - they felt the patter between the soldiers was very real. It's funny how it all snowballed."
Bbc Scotland have been deliberately vague with details about One Night In Emergency.
Burke, however, has admitted he was aiming for something "mythical", like Homer's The Odyssey "set within a hospital environment with surreal twists and turns."
And the script immediately appealed to the 36-year-old actor.
Kevin said: "I really liked it. I thought it was weird and strange, something I couldn't quite get my head around at first.
"Since then, we've got to the point when I've managed to make some sort of sense from it. It gets into dark areas, and is much darker than things you'd get on the American network."
Kevin is called back on set for a short scene at the end of the corridor. When he returns, his eyes appear red raw.
"I'm supposed to be not very well," he said. "But I can't say much more than that. Things appear quite normal on the surface, but there's more to it than that.
"At first, it looks like it's going to be a kitchen sink drama about the state of the NHS, but then quickly we realise there are far stranger things going on.
"It's very in vogue at the moment to have this hyper-real gritty drama and that's one of the things that attracted me to it."
Trial & Retribution's David Hayman also figures, as does Sanjeev Kohli and Kevin's old Trainspotting buddy Ewen Bremner.
Kevin said: "Ewen and I have stayed in touch over the years. We were in 16 Years of Alcohol and The Acid House together, but it was great to see him again.
"I've started to become aware of the passage of time, though, because there are crew members who are actually too young to remember Trainspotting, and that's quite a thought. It's almost become a museum piece."
The same can be said for his sci-fi venture Journeyman, which was cancelled mid-run because of mediocre viewing figures and the writer's strike.
For now, though, he has plenty to detain him.
One Night In Emergency was followed by a whistle-stop tour of the Hebrides and Western Isles with his wife.
After that, the open-ended arrangement in Grey's Anatomy means he's sorted for work in the short term.
"The contracts are all swayed in favour of the studios," he said. "How long it lasts is beyond my control."
As is the impact the phenomenally popular series has, as he discovered after only a few weeks as Dr Hunt.
He said: "We were invited to the premiere of Frost/Nixon in Hollywood. So me and my wife were getting our pictures taken on the red carpet and suddenly the paparazzi at the end of the line went mental.
"Then this tall, glamorous woman went past us, took me by the arm and told me she loved my character in Grey's Anatomy. My wife was like, 'That was Sharon Stone!'
"I wasn't at the right angle to check whether she was wearing her underwear, though..."
One Night In Emergency, BBC1, Monday, 9pm
*correction Kevin comes from Elgin and not Nairn(tks to Graeme from our Facebook Page)