Owen began the episode treating a carjacking victim with Jo Wilson. When Callie Torres was called in to evaluate the patient's orthopedic injuries it was good she was there as they needed an extra set of expert surgeon's hands when the severity of the patient's injuries drew grave. Soon thereafter we discovered that her coworkers found her in their company parking lot and were concerned enough to call an ambulance yet none of them knew her well enough to suggest a family member to contact regarding her condition. During surgery Callie discovered the patient had a tattoo which indicated she'd served in the Iraq war.
Once the police arrive with news that their carjacking patient's car was found in pieces and her belongings were lost, it triggered Jo's realization that their patient was living in her car as Jo herself had done as a young woman. Owen's heartbroken reaction was evident as he realized the truth of what Jo was saying. He was clearly touched that a veteran who had served in the same war in which he'd served two tours had such few personal resources and had been treated so badly.
While Melissa was reluctant to accept help and remained certain she could handle things on her own as she always had, Owen convinced her by revealing his own army connection that it was a sign of strength to allow other people in when you're struggling. Even though Cristina Yang's name wasn't mentioned, it was a nice harkening back to a previous Season 11 speech from Owen about how the darkness the war put in him was lit up by letting someone in and accepting help and that in doing so he'd had the ability to forge a new life for himself.
Elsewhere in the hospital: the stilted conversation between Maggie Pierce and Meredith Grey drove Derek to plan a 'family-ish' dinner which included Richard Webber; Jackson Avery arrived at the hospital with April Kepner's mother which flustered her as she tried to run the trauma department; Jackson ended up bonding with Mrs. Kepner; April eventually found common ground with her mom during this visit; Callie and Arizona Robbins interacted hesitatingly about their split; additionally, Arizona continued to work with her mentor Dr. Herman who it turned out had a terminal illness which explained her mercurial and intense work style; Alex Karev encouraged Arizona to trust her abilities; Jo found herself triggered by treating a homeless patient; Ben, and the patient case they worked on together, encouraged Miranda Bailey to take better care of herself; and Maggie confronted Richard when he tried to reach out to her.