What's Next: Season 13 will primarily focus on the original characters of Meredith, Alex, Bailey and Richard. The Meredith-Riggs-Maggie dynamic will cause problems for the sisters beyond the season premiere, which will mainly deal with the "pretty intense fallout" from Alex's beating of DeLuca, which "causes some friction among the doctors," Kelly McCreary tells TVGuide.com. Amelia and Owen will find themselves navigating the ups and downs of married life, while Alex and Jo find their relationship upended after Jo's dishonesty and Alex's violent impulses. It remains to be seen whether Callie will get a proper sendoff, given Sara Ramirez's departure from the show, as well as whether Jackson and April's co-parenting will reunite them as a couple.
Photo by: Kelsey McNeal/ABC